Better understand the tablet capping lamination phenomenon.
Tablet capping and lamination.
Fines are small dust particles which.
Root causes of lamination.
First lamination is caused by air being trapped in the tablet especially among the granules or particles.
Using acetaminophen containing formulations we examined the potential use of a compaction simulator as a material sparing tool to predict capping occurrence under commercial.
Although the method is widely used there are still significant challenges with achieving a high quality compact.
Lamination is whenever tablet is breaking or separating anywhere rather than top if is separating from top it is capping.
This is the problem faced in the formulation of the granules.
Lamination is also caused by the presence of a large amount of fines in the granulations.
Before rectifying be sure it is lamination where is the problem surface of tablet below the top layer or bottom of tablet.
The following are some of the common factors which can cause tablet capping.
This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate.
Machine related in this article we will be discussing five major causes of this problem and remedies for them.